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Shift Work

I had taken Provigil daily for a couple months earlier this year without any significant side effects, and was very happy with it.

It’s effective for me in increasing my alertness and giving me more mental clarity through the day.

I believe it also helped me through a difficult grieving process in lifting my mood somewhat.

Ideopathic Hypersomnia

This was self-medication as GP had no answers for bad sleep.

Rather than use a sleeping pill, I tried modafinil to wake myself up.

No systematic effect on hunger.

Incredibly effective if short of sleep for a day or two.

Very productive, brain very clear – things that had puzzled me got sorted very quickly (maths stuff!) and raced through design and analysis (I’m an engineer).

Some mood lift, not manic, definitely more sociable, positive and confident.

After a couple of months I got very tired & thought I might have damaged myself, took a break for a week felt normal again and found brain was back on-form :)

I find I can sleep perfectly well if still affected at the end of the day though tend to wake early feeling I’ve had enough sleep.

The much-vaunted “focus” can make it hard to change to other tasks.

It’s also a bit hard to manage: the effects run into the night so you end up short of sleep again unless you force yourself to go to bed.

Get a bit crazy if you run short of sleep for several days running – flights of fancy, slight peripheral vision effects (of the “was that a bug flying past?” sort), just like being over-tired (like I am now) – which you are though you don’t feel sleepy.

(A short nap clears the head and then you need to force yourself to go to bed at a sensible time!)

I find 100mg will dispel my usual tendancy to doze off (or most of it), 200 is nice, 400 does get a bit manic, I suppose that’s when the stimulant effects starts.

Almost immediately, I had energy.

I was able to play with my kids all day.

My patience and mood are much improved.

Yet I can easily take a nap if I need to ( after a long day at the beach in the waves).

I feel like myself again! I am so grateful!

Excessive Sleepiness

It seems to do what it should.

It keeps me awake all through the day.

I operate heavy equipment from time to time as part of my job and it does not seem to effect my level of concentration at all.

I have done some research and found that taking a “drug holiday” or going a day or two out of the week with out it will help it stay just as potent as the first time I used it.

I have also noticed that when I work out a couple times a week a smaller dose is required to do the same job and for what ever reason the weight seems to come off faster.

On the bad side at times I feel as though my brain is numb similar to taking too much cold medicine.

Also I can usually fight off sleepyness later in the day as long as I stay physically active.

If I come home and sit down for any length of time I’m usually fighting to stay awake.

Anxiety, Depression

I was prescribed provigil as, after 10yrs+ of extreme exhaustion as part of my recurrent treatment resistant depression, my psych was clutching at straws!

The funny thing is I can still sleep through a provigil dose if I want to (although if I do get out of bed I am much more lucid) but I have experienced the most amazing lift in my mood.

Within 10 days of taking provigil I genuinely felt like the cloud which has been over my head for 10 years started to get a bit thinner.

9 months later and I still feel it gives me a lift.

I could not function without this medicine.

It has helped my attention issues and depression – when I take this in the morning, I know I am going to have a great day – no fatigue, helps with appetite control and depression.

Chronic Fatigue

I can’t function without taking Provigil.

I had to stop taking it when I was pregnant and nursing.

During that time, my boss thought I was severely depressed and hated my life.

In reality, I was just constantly battling to stay awake.

Like someone else said, you feel sedated- fighting your hardest to stay awake.

I hate to rely on meds to function in life, but it’s not an option.

The only problem I’m having now is that the effects aren’t as long lasting.

My neurologist added Adderall to my daily routine, but I can’t tell a difference- besides the loss of appetite (which I like).

Provigil used to get me through at least the work day, but now it only lasts a couple of hours before I’m falling asleep at my desk again.

Without taking the entire daily dose in the morning, I can’t fully wake up, which leaves me struggling by 10am.

So I take another one to get through another couple hours, even though it’s not prescribed at that dosage.

It does have a sudden stopping affect, not a slow come down.

I’ve noticed when I don’t take it, I eat everything in site all day long…when I’m not sleeping.

Right now I’m praying for a miracle drug, because I don’t want to reach the max dose for this and it not work anymore.

Attention / Concentration Issues

I started Providgil 3 months back to treat my ADD/concentration issues.

I was originally put on Ritilan in 5th grade and then went on Adderall and Dexedrine in high school and college.

I had substance abuse problems that were exacerbated by these meds and eventually had to come off everything and get clean.

Now, 6 years later, still clean and sober I found my attention issues to be an issue again.

I first tried Strattera which was a completely bogus drug.

It made my symptoms worse, and had *several* unpleasant side effects.

I tried Wellbutrin which worked great for a while, but stopped it after the max dose started to lose its effect.

I reluctantly started on Providgil 3 months ago, I stayed away from it because it was a controlled substance.

Now that I’ve been on it for 3 months I’m having difficulty understanding why it’s controlled.

It definitely wakes you up but doesn’t provide a ton of euphoria.

I honestly felt more euphoric on Wellbutrin (which isn’t controlled).

Bottom line is the drug worked really well for me at first, but it’s starting to lose its efficacy; just like everything else…And I’m at the max dose of 600mg a/day.

My doctor is suggesting adding Wellbutrin back in to the mix, so we will see.

I’m curious if anyone else has had a similar experience, I’m doing whatever I can to avoid anything in the ritian/amphetamine class of drugs.

I will also add that regular exercise and a diet low in carbohydrates high in protein have helped a lot too.

 

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Modafinil

1. Provigil®

2. Modalert®

3. Modapro®

4. Alertec®

Modafinil (Generic Provigil®, Alertec®, Modalert®) is an analeptic drug and is approved by the U.S. Food and Drug Administration (FDA) for the treatment of narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea.


Dapoxetine

1. Priligy®

Dapoxetine (Generic Priligy®): Premature ejaculation refers to a condition where, during sexual intercourse, a man ejaculates too soon before his partner can achieve orgasm.

It often remains neglected and un-treated.

PE can occur to any age group and under any situation.

The results of studies treating PE with dapoxetine are compelling.

They demonstrate that, for the first time, a medicine can be taken by men on an on-demand basis and provide significant improvement in their premature ejaculation condition.

Studies indicate that on average, ejaculation is delayed by up to 400% when Dapoxetine is taken as directed.

Side effects from the drug were mild and infrequent.

Take one tablet 30 mins to 2 hours before sexual intercourse.


Sibutramine

1. Meridia®

2. Reductil®

Sibutramine (generic Meridia® , Ectiva®, Reductil® is an orally administered agent for the treatment of obesity, as an appetite suppressant.

It works by acting on appetite control centers in the brain to decrease appetite.


Tramadol

1. Ultram®

Tramadol (generic Ultram®) is a centrally acting analgesic, used for treating moderate to severe pain.

Tramadol acts centrally (in the brain) to modulate the sensation of pain and has no anti-inflammatory effect.

It is a good option for treatment of pain because patients do not build up a tolerance with extended usage and there is a very low incidence of addiction.


Fluoxetine

1. Prozac®

Fluoxetine (generic Prozac®) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Fluoxetine is approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, anorexia nervosa, panic disorder and premenstrual dysphoric disorder.

Despite the availability of newer agents, it remains extremely popular.

Over 22.2 million prescriptions for generic formulations of fluoxetine were filled in the United States in 2007, making it the third most prescribed antidepressant


Sertraline

1. Zoloft®

2. Lustral®

Sertraline hydrochloride (generic Zoloft®, Lustral®) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

Sertraline is primarily used to treat major depression in adult outpatients as well as obsessive–compulsive, panic, and social anxiety disorders in both adults and children.

In 2007, it was the most prescribed antidepressant on the U.S. retail market, with 29,652,000 prescriptions.


Escitalopram

1. Lexapro®

2. Cipralex®

Escitalopram (generic Lexapro®, Cipralex®) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

It is approved for the treatment of major depressive disorder and generalized anxiety disorder; other indications include social anxiety disorder, panic disorder and obsessive-compulsive disorder.


Celecoxib

1. Celebrex®

2. Celebra®

Celecoxib (Generic Celebrex®, Celebra®) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the symptoms of osteoarthritis and rheumatoid arthritis in adults.

It may also be used to treat acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis.


Sumatriptan

1. Imitrex®

2. Imigran®

Sumatriptan (Generic Imigran®, Imitrex®), taken at the beginning of a migraine headache, may reduce the severity of the headache.

It is not effective in preventing migraines.

It can also stop the upset stomach, vomiting, and sensitivity to light and noise associated with migraine headaches.


Carisoprodol

1. Soma®

2. Sanoma®

3. Carisoma®

Carisoprodol, (Generic Soma®) is a muscle relaxant, and is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries.

This medication is sometimes prescribed for other uses; ask your doctor for more information.

Carisoprodol comes as a 350mg tablet to take by mouth. It usually is taken three times daily and at bedtime.

It may be taken with or without food.


Zaleplon

1. Sonata®

2. Starnoc®

Zaleplon (generic Sonata®, Starnoc®) is a sedative/hypnotic, mainly used for insomnia.

It is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class.

Zaleplon is one of few sleep medications which have been found to not cause an increase in road traffic accidents, thus demonstrating a much higher safety profile than many other hypnotics currently on the market.


Finasteride

1. Propecia®

1. Proscar®

Finasteride (generic Proscar®, Propecia®) is used in the treatment of prostate cancer, benign prostatic hyperplasia and androgenetic alopecia (male-pattern baldness).

Finasteride (generic Proscar®, Propecia®) prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body.

DHT is involved in the development of benign prostatic hyperplasia (BPH) and hair loss.


Tadalafil

1. Cialis®

Tadalafil (Generic Cialis®) Erectile Dysfunction, (Impotence), is the persistent inability to achieve and maintain an erection sufficient to complete sexual intercourse.

Tadalafil is taken orally as needed prior to sexual activity (about one hour before is most effective).

Tadalafil works along with sexual stimulation to help achieve an erection.

Your results may vary, but for some men, Cialis® (tadalafil) often works within 30 minutes and stays effective for up to 36 hours.


Sildenafil Citrate

1. Viagra®

Sildenafil Citrate (Generic Viagra®) Erectile Dysfunction, (Impotence), is the persistent inability to achieve and maintain an erection sufficient to complete sexual intercourse.

Sildenafil is taken orally as needed between four hours and one-half hour before sexual activity (about one hour before is most effective).

Take only as directed, usually once daily as needed.

Sildenafil works along with sexual stimulation to help achieve an erection.

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Amphetamine

Because Modafinil acts on a different part of the brain than amphetamines, people who take Modafinil to stay awake for long periods of time don’t get the jitters, nervousness, or shakes.

There is no “crash” when Modafinil wears off, so a person taking Modafinil should be able to sleep normally.

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Although Modafinil is not regulated for off-label use, many applications for this medication can be noted.

The availability of Modafinil online makes it possible for people who don’t have health insurance or a regular family physician to benefit from the effects of this very effective and safe stimulant.

Modafinil is used widely “off-label” to suppress the need for sleep.

It is also used off-label in combating general fatigue unrelated to lack of sleep such as in treating ADHD and as an adjunct to antidepressants (particularly in individuals with significant residual fatigue).

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Difficulty Sleeping

Modafinil is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) or shift work sleep disorder (sleepiness during scheduled waking hours.

SWSD also encompasses the problems of difficulty falling asleep or staying asleep during scheduled sleeping hours in people who work at night or on rotating shifts).

Modafinil is in a class of medications called wakefulness promoting agents and is not an amphetamine.

Modafinil works by changing the amounts of certain natural substances in the area of the brain that controls sleep and wakefulness.

Modafinil has a pharmacological profile that is notably different from amphetamines and methylphenidate (Ritalin).

Current research suggests Modafinil is a safe, effective and well-tolerated agent much like its older and better-tested analogue Adrafinil.

Some benefits of Modafinil is that it is long-acting and doesn’t tend to cause peripheral sympathetic stimulation like insomnia.

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Here is a post from a Modafinil/Provigil forum that pretty much describes the effects of Modafinil,

the good and the bad…

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I’m 32 and diagnosed with mild narcolepsy.

Prescribed 200mg of provigal in the morning, and another 200mg at lunch (if needed).

The drug is like a sword with two edges:

Edge 1

1. improved memory
2. extra energy all day long
3. feeling of mild euphoria
4. reduces stress/ anxiety
5. you feel driven

Edge 2

1. take too much you get hyper
2. dont sleep enough feel like a zombie on it
3. hyper focus
4. headaches
5. nausea
6. loss of apetite
7. if you smoke, you’ll feel like smoking alot more
8. no alcohol – you feel dizzy, not good feeling
9. you get angry, your driving at 100 in a 60 zone all day long…a new feeling
10. your personality will change not by choice
11. you get depressed about the past mainly missed opportunities because you wern’t on Provigal.
11. it’s not addictive, so choose…walk around like a slow dim witted moron always sleepy or focused, energised and happy ready to take on the world.

 

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Modafinil is the active ingredient in Modafinil online.

Modafinil is marketed under the brand and generic names Provigil, Alertec, Modavigil, Modalert, Modiodal, Modafinilo, Carim and many others.

Modafinil is an analeptic drug (a central nervous system (CNS) stimulant medication) manufactured by Cephalon (Provigil brand only), and is approved by the U.S. Food and Drug Administration (FDA) for the treatment of narcolepsy, shift work sleep disorder (SWSD), and excessive daytime sleepiness associated with obstructive sleep apnea.

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The exact mechanism of action of Modafinil is unclear, although numerous studies have shown it to increase the levels of various chemicals in the brain called monoamines.

Only a few specific areas of the brain are affected by Modafinil causing an increase in certain chemical production, they are:

  • Dopamine – in the striatum and nucleus accumbens
  • Noradrenaline – in the hypothalamus and ventrolateral preoptic nucleus
  • Serotonin – in the amygdala and frontal cortex

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Although Modafinil is not regulated for off-label use, many applications for this medication can be noted.

The availability of Modafinil online makes it possible for people who don’t have health insurance or a regular family physician to benefit from the effects of this very effective and safe stimulant.

Modafinil is used widely “off-label” to suppress the need for sleep.

It is also used off-label in combating general fatigue unrelated to lack of sleep such as in treating ADHD and as an adjunct to antidepressants (particularly in individuals with significant residual fatigue).

Modafinil is also used off-label to treat sedation and fatigue in:

  • Depression
  • Fibromyalgia
  • Chronic Fatigue Syndrome
  • Myotonic Dystrophy
  • Opioid-Induced Sleepiness
  • Spastic Cerebral Palsy, and
  • Parkinson’s Disease

It increases subjective mood and friendliness, at least among shift workers.

It has been used to help with jet-lag.

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